Eastern Michigan University
Eastern Michigan University


Catherine Kaminski in the lab.


*denotes student author

Chumki SA*, Dunn MK*, Coates TF*, Mishler JD*, Younkin EM, and Casper AM. Remarkably Long-Tract Gene Conversion Induced by Fragile Site Instability in Saccharomyces cerevisiae. Genetics (2016) 204(1):115-28.[link to article]

Rosen DM*, Younkin EM, Miller SD*, and Casper AM. Fragile Site Instability in Saccharomyces cerevisiae Causes Loss of Heterozygosity by Mitotic Crossovers and Break-Induced Replication. PLOS Genetics (2013) 9(9):e1003817. doi: 10.1371/journal.pgen.1003817. [link to article]

Casper AM, Rosen DM*, and Rajula KD*. Sites of genetic instability in mitosis and cancer. Annals of the New York Academy of Sciences (2012) 1267:24-30.(conference issue).[PDF]

Casper AM, Greenwell PW, Tang W and Petes TD. Chromosome aberrations resulting from double-strand DNA breaks at a naturally-occurring yeast fragile site composed of inverted Ty elements are independent of Mre11p and Sae2p. Genetics (2009) 183:423-39. [PDF]

Casper AM. Colon Cancer: A Case of Genetic Bad Luck? Web-based Case Study Collection of the National Center for Case Study Teaching in Science at the State University of New York at Buffalo (2008).
[Case student handouts] [Case teaching notes]

Casper AM, Mieczkowski PA, Gawel M and Petes TD. Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae. PLoS Genetics (2008) 4(6): e1000105 doi:10.1371/journal.pgen.1000105 [link to article]

Casper AM, Arlt MF, and Glover TW. "Common Fragile Sites: Cytogenetics and Cell Cycle Checkpoints." Fragile Sites: New discoveries and changing perspectives. Eds. Isabel Arrieta, Olga Penagarikano, Mercedes Telez. Nova Science Publishers Inc., Hauppauge, NY (2007), pp. 47-66. [invited review]

Miller CT, Lin L, Casper AM, Lim J, Thomas DG, Orringer MB, Chang AC, Chambers AF, Giordano TJ, Glover TW and Beer DG. Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma. Oncogene (2006) 25:409-18. [PDF]

Glover TW, Arlt MF, Casper AM and Durkin SG. Mechanisms of common fragile site instability. Human Molecular Genetics (2005) 14 (Supp. 2):R197-R205. [PDF]

Casper AM, Durkin SG, Arlt MF and Glover TW. Chromosomal Instability at Common Fragile Sites in Seckel Syndrome. The American Journal of Human Genetics (2004) 75:654-60. [PDF]

Arlt MF, Xu B, Durkin SG, Casper AM, Kastan MB and Glover TW. The BRCA1-dependent G2/M checkpoint pathway is crucial to common fragile site maintenance. Molecular and Cellular Biology (2004) 24:6701-6709. [PDF]

Arlt MF, Casper AM and Glover TW. Common Fragile Sites. Cytogenetic and Genome Research (2003) 100:92-100. [invited review] [PDF]

Casper AM, Nghiem P, Arlt MF and Glover TW. ATR Regulates Fragile Site Stability. Cell (2002) 111:779-789. [PDF]

Harshman, Lawrence G., Loeb, Anne M. and Johnson, Beth A. Ecdysteroid titers in mated and unmated Drosophila melanogaster females. Journal of Insect Physiology (1999) 45: 571-577. [PDF]